Clinical Trials

The Influence of Motor Control Instruction and Taping on Center of Pressure and Scapulothoracic Kinematics during Reaching for Individuals with Hemiparesis           
Principal Investigator:                 Suzanne Babyar, PT, PhD     (BRC 328)

Comparison of Physical Therapy Interventions for Individuals with Lateropulsion following Stroke.
Principal Investigator:                Suzanne Babyar, PT, PhD     (BRC 329)

Effects of Electrical Stimulation to Neck Muscles on Unilateral Neglect Following Stroke.
Principal Investigator:               Suzanne Babyar, PT, PhD     (BRC 363)

Molecular Genetic Factors in Dementing Disorders
Principal Investigator:              John Blass, MD, PhD        (BRC 267)

An Observational Study of Women Previously on the Prempro/Placebo Controlled Trials of Estrogen to Prevent Alzheimer’s Disease and Loss Of Memory in Women.
Principal Investigator:             John Blass, MD, PhD         (BRC 349)

A Randomized Double-Blind Placebo Controlled Evaluation of The Safety & Efficacy of Memantine in Patients with Moderate to Severe Dementia of the Alzheimer Type. Protocol No. MEM-MD-50
Principal Investigator:            John Blass, MD                (BRC 361)

SNP Based Fine Mapping of Autopsy Proven Alzheimer Disease Families
Principle Investigator:           Abraham M. Brown, PhD   (BRC 365)

The Predictive Validity of RBANS for Long-Term Outcome in Traumatic and Non Traumatic Brain Injured Patients.
Principal Investigator:           George Cuesta, PhD              (BRC 332)

Placebo Controlled Trial of Botox vs Zanaflex for the Treatment of Subjects With Post Stroke Upper Limb Spasticity.
Principal Investigator:           Pasquale Fonzetti, MD          (BRC 333)

PRoFESS-Prevention Regimen for Effectively Avoiding Second Strokes: A Double-Blind, Active and Placebo Controlled Study of Aggrenox®  vs Clopidogrel  with and without Micardis®.
Principal Investigator:           Pasquale Fonzetti, MD          (BRC 351)

Investigator: Insulin Resistance Intervention after Stroke (IRIS) Trial.
Principle Investigator:          Pasquale Fonzetti, MD          (BRC 364)

Walking Study for Inpatient Stroke Rehabilitation
Principle Investigator:           Pasquale Fonzetti, MD          (BRC 375)

a- Ketoglutarate Dehydrogenase in Neurodegeneration.
Principal Investigator:           Gary Gibson, PhD                  (BRC 292)

Mitochondrial Enzymes and Oxidative Stress in Alzheimer’s Disease.
Principal Investigator:           Gary Gibson. PhD                  (BRC 293)

Comparison of Gait Training Strategies for Individuals with Transtibial Amputations.
Principle Investigator:           Nannette W. Hyland, PT       (BRC 359)

Molecular Genetic Factors in Rehabilitation.
Principle Investigator:           Barry Jordan, MD                 (BRC 296)

A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Phase 2 Study To Evaluate the Safety and Efficacy of FK962 in Subjects with Mild to Moderate Alzheimer’s Disease. Protocol No. 030-0-189
Principal Investigator            Barry Jordan, MD                 (BRC 353)

A 12 week, Multicenter, Open-Label Study to Evaluate the Effectiveness & Safety of Donepezil Hydrochloride (Aricept) in Hispanic Patients with Mild to Moderate Alzheimer’s Disease.
Principle Investigator:           Barry Jordan, MD                 (BRC 366)

A Double Blind Placebo Controlled Study of VP4896 for the Treatment of Mild-to-Moderate Alzheimer’s Disease.
Principle Investigator:           Barry Jordan, MD                 (BRC 367)

An Open Label Extension Study Evaluating the Safety and Tolerability of Memantine in Patients Moderate to Severe Dementia of the Alzheimer’s Type Protocol  No. MEM-MD-54.
Principle Investigator:           Barry Jordan, MD                 (BRC 368)

Perception of Quality of Life by Chronic Obstructive Pulmonary Disease Patients after Occupational Therapy
Principle Investigator:           Adrienne Marco, OTS           (BRC 362)

Treatment Effectiveness in Depressed patients with COPD.
Principle Investigator:           Richard Novitch, MD            (BRC 316)

Treating Older Patients with Major Depression and Severe COPD.
Principle Investigator:           Richard Novitch, MD            (BRC 374)

Amphetamine Enhanced Stroke Recovery.
Principal Investigator:           Meheroz Rabadi, MD           (BRC 300)

Impact of Aggressive Treatment of Undernutrition on Functional Outcome Measures in Stroke Patients on an Acute Rehabilitation Unit.
Principal Investigator:           Meheroz Rabadi,MD             (BRC 343)

Comparison of Upper Body Ergometer vs. Robot in Upper Extremity Functional Motor Recovery.
Principal Investigator:           Meheroz Rabadi, MD            (BRC 357)

To Study the Effect of interpersonal Group Intervention on stroke Patients with Major Depression. 
Principal Investigator:           Meheroz Rabadi, MD            (BRC 358)

A Pilot Trial of an Antioxidant/Metabolic Treatment of Stroke.           
Principle Investigator:           Meheroz H. Rabadi, MD      (BRC 371)

Comparison of Physical Therapy Interventions for Individuals with Lateropulsion following Stroke.
Principal Investigator:           Michael Reding, MD                        (BRC 329)

Effectiveness of Fitness Program Following Stroke.
Principal Investigator:           Sudhir Vaidya,MD                            (BRC304)

Correlation between anxiety, depression and somatization on total hip and knee replacement outcomes.
Principle Investigator:           Sudhir Vaidya, MD                (BRC 369)

The Effect of Interactive Robotic manipulation on Upper Arm Paralysis.
Principal Investigator:           Bruce Volpe, MD                  (BRC 227)

The Effect of Controlled Environment or Robotic Training or Both on the Functional Magnetic Resonance Images in Patients Recovering Upper Limb Motor Ability Following Stroke
Principal Investigator:   Bruce Volpe, MD                  (BRC 319)

Evaluation of 3-D Robotic Upper Extremity Neuro-Rehabilitation In Out-patients with Stroke.
Principal Investigator            Bruce Volpe, MD                  (BRC 324)

The Effect of Ankle CPM in Post Acute Stroke
Principle Investigator:           Bruce Volpe, MD                  (BRC 344)

Pilot Study of Pharmacological and Robotic Intervention in Stroke Recovery.
Principle Investigator:           Bruce Volpe, MD                  (BRC 355)

Evaluation of Wrist Robotic Device in Out-patients With Stroke.
Principle Investigator:           Bruce Volpe, MD                  (BRC 376)

Evaluation of Shoulder-Elbow and Wrist Robotic Device in Patients With Spinal Cord Injury.
Principle Investigator:           Bruce Volpe, MD                  (BRC 377)         

Evaluation of Combination Treatment with Transcranial Direct Current Stimulation (TDCS) and Wrist Robot Device in Outpatients with Stroke: Pilot Project
Principle Investigator:           Bruce Volpe, MD                  (BRC 378)

Evaluation of combination treatment of wrist robot device with pre-training standard theophylline in out-patients with stroke.
Principle Investigator:           Bruce Volpe MD                   (BRC 379)

Rehabilitation following Total Knee Replacement, Total Hip Replacement and Hip Fx.: A Site Comparison.
Principle Investigator:           Mary Beth Walsh, MD         (BRC 370)

An Exploratory Pilot Investigation of Cardiac and Pulmonary Outcomes in Inpatient Rehabilitation versus Skilled Nursing Facilities
Principle Investigator:           Mary Beth Walsh, MD         (BRC 373)

Biomarkers for StrokeRecovery                                                         
Principle Investigator:           Rajiv Ratan, MD, PhD          (BRC 382)