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Pioneering Rehabilitation

Dr. Gibson and Dr. Shi Co-author Chapter on the Role of Mitochondria in Age-Related Diseases

Published July 3, 2012

Gary Gibson, Ph.D., director of Burke's Laboratory for Mitochondrial Biology and Metabolic Dysfunction in Neurodegeneration, and his laboratory member Qingli Shi, Ph.D., along with with two colleagues in the department of neurology at Weill Cornell Medical College, co-authored the chapter “α-Ketoglutarate Dehydrogenase Complex in Neurodegeneration” in the book Mitochondrial Signaling in Health and Disease, edited by Sten Orrenius, Enrique Cadenas and Lester Packer.

Mitochondria are sub-cellular organelles in cells that provide the cells’ energy and release many proteins that can promote cell death. The chapter describes research done at Burke on the role of mitochondria in age-related diseases including Alzheimer’s disease, Huntington’s disease and Parkinson’s disease. The chapter shows how this reveals new therapeutic approaches to treating mitochondrial deficits.