Take the Henry Hudson north, Major Deegan (I-87) north, Bronx River Parkway north, Hutchinson River Pkwy north, or I-95 North.

For Henry Hudson Parkway 
Take the Henry Hudson Parkway north to the Cross County Parkway east to the Hutchinson River Parkway north. Exit at 23N onto Mamaroneck Ave and continue for five traffic lights to Heatherbloom Road. Turn right and Burke's entrance in on your immediate left. (If you pass Bryant Avenue you have gone too far.)

For I-95 
Take I-95 north to the Hutch northbound to exit 23N and follow Mamaroneck Ave.as directed above. Or continue past the Hutch on I-95 to exit 18B (3rd exit after toll). Stay right off of exit, north on Mamaroneck to Heatherbloom Road and turn right. Burke is on your immediate left. (If you pass Bryant Avenue you have gone too far.) 
 

For the Major Deegan or Bronx River Parkway
Proceed north to the Cross County Parkway east to the Hutchinson River Parkway North, to exit 23N. Take Mamaroneck Ave. north for five traffic lights and turn right onto Heatherbloom Road. Burke is on your immediate left. (If you pass Bryant Avenue you have gone too far.)

For the Hutchinson River Parkway 
Take the Hutchinson River Parkway North to Exit 23 N. Proceed on Mamaroneck Avenue for 5 lights. Turn right onto Heatherbloom Road. The entrance to Burke is on your immediate left. (If you pass Bryant Avenue you have gone too far.)

Garden State Parkway to NY Thruway to Tappan Zee Bridge. Cross the Tappan Zee Bridge on the N.Y.S Thruway to 287 East. Use Exit 9A Westchester Ave. Make right at first light, Bryant Avenue. Proceed 4 lights to Mamaroneck Avenue. Make left onto Mamaroneck Ave.First light make left onto Heatherbloom Road. Make your immediate left into Burke

I-95 South
Take I-95 South to I-287 West. Exit 9S to the Hutchinson River Parkway South. Use Exit 23 North. Proceed on Mamaroneck Avenue for 5 traffic lights. Make a right, entrance to Burke is on immediate left.

Merritt Parkway or I-684 
Take Merritt Parkway or I-684 South to Hutchinson River Parkway South. Use Exit 23 North. Continue for five traffic lights to Heatherbloom Road. Turn right and Burke's entrance in on your immediate left. (If you pass Bryant Avenue you have gone too far.)

Go south on 684 to the Hutchinson River Parkway. Use Exit 23 North. Continue for five traffic lights to Heatherbloom Road. Turn right and Burke's entrance in on your immediate left. (If you pass Bryant Avenue you have gone too far.) 

You may also go south on 684 exiting at White Plains/Rte. 287 West. Stay on Westchester Avenue to first traffic light.  Turn left crossing over bridge (crossing over 287) and left at the light onto Westchester Ave. Make a right at the next light onto Bryant Ave.At the fourth light make a left onto Mamaroneck Ave.Go one block to traffic light at Gedney Way/Heatherbloom Rd. Turn left onto Heatherbloom; The Burke entrance is on the immediate left.

Take the Beeline bus to White Plains Trans-Center. Then take bus number 60/63 to Burke.

Take Metro North to the White Plains train station.  Then take bus number 60/62 to Burke.